Macroautophagy

{
  "id": "MLC-T-CHM-006860",
  "term": "Macroautophagy",
  "field": "Chemistry",
  "definition": "A cellular process involving the formation of a double-membraned vesicle, called an autophagosome, which engulfs cytoplasmic components, including damaged organelles and protein aggregates. This autophagosome then fuses with a lysosome, leading to the degradation of its contents and the recycling of molecular building blocks. It is a major pathway for cellular self-digestion and quality control.",
  "synonyms": [
    "non-specific autophagy"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "phagolysosome",
    "autophagy",
    "lysosome"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1207 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/macroautophagy/"
}