Measurement procedure with standard addition

{
  "id": "MLC-T-CHM-007100",
  "term": "Measurement procedure with standard addition",
  "field": "Chemistry",
  "definition": "An analytical technique where the sample is analyzed before and after adding known amounts of the analyte, called standards. A calibration curve is constructed by plotting the instrument response against the concentration of the added standard, allowing the initial concentration in the unknown sample to be determined by extrapolation. This method is distinct from external calibration, where standards are prepared in a separate matrix-free solvent.",
  "synonyms": [
    "standard addition"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "measurement procedure",
    "multiplicative matrix effect"
  ],
  "references": [
    "PAC, 2021, 93, 997. 'Metrological and quality concepts in analytical chemistry (IUPAC Recommendations 2021)' on page 1012 (https://doi.org/10.1515/pac-2019-0819)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/measurement-procedure-with-standard-addition/"
}