Methylation

{
  "id": "MLC-T-CHM-007280",
  "term": "Methylation",
  "field": "Chemistry",
  "definition": "A biochemical process involving the addition of a methyl group (CH3) to a substrate molecule. This modification can occur on DNA, proteins, or other organic compounds, influencing their function and activity. In epigenetics, DNA methylation at cytosine residues within CpG islands regulates gene expression without altering the underlying DNA sequence.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 779 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/methylation/"
}