Microheterogeneity

{
  "id": "MLC-T-CHM-007336",
  "term": "Microheterogeneity",
  "field": "Chemistry",
  "definition": "The existence of multiple molecular forms of a glycoprotein or other biomolecule that differ slightly in their carbohydrate chains or other post-translational modifications. These variations arise from incomplete processing or alternative glycosylation pathways during synthesis. This phenomenon can influence the biological activity, stability, and immunogenicity of the molecule.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "glycopeptides"
  ],
  "references": [
    "PAC, 1988, 60, 1389. 'Nomenclature of glycoproteins, glycopeptides and peptidoglycans (Recommendations 1985)' on page 1391 (https://doi.org/10.1351/pac198860091389)",
    "White Book, 2nd ed., p. 86 (https://iupac.qmul.ac.uk/bibliog/white.html)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/microheterogeneity/"
}