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Nondepleting antibody

Term · Chemistry · MLC-T-CHM-008016

An antibody that binds to a target cell without causing its destruction or removal from circulation. These antibodies are designed to modulate cell function or block receptor activity rather than eliminate the cell. This contrasts with depleting antibodies, which typically induce cell lysis or phagocytosis.

Table 1. Record
IdentifierMLC-T-CHM-008016
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1221 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoB lymphocyte; Killer cell
Record as JSON
{
  "id": "MLC-T-CHM-008016",
  "term": "Nondepleting antibody",
  "field": "Chemistry",
  "definition": "An antibody that binds to a target cell without causing its destruction or removal from circulation. These antibodies are designed to modulate cell function or block receptor activity rather than eliminate the cell. This contrasts with depleting antibodies, which typically induce cell lysis or phagocytosis.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "killer cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1221 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/nondepleting-antibody/"
}

Record 8,510 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.