Papanicolaou smear

{
  "id": "MLC-T-CHM-008431",
  "term": "Papanicolaou smear",
  "field": "Chemistry",
  "definition": "A cytological screening method for detecting precancerous and cancerous conditions of the uterine cervix. The procedure involves collecting exfoliated cells from the cervix, which are then fixed, stained using the Papanicolaou method, and examined under a microscope for abnormalities in cell morphology. This specific staining technique uses a combination of hematoxylin, Orange G, and eosin azure to highlight features of the cell nucleus and cytoplasm, aiding in the identification of dysplasia.",
  "synonyms": [
    "cervical smear",
    "Pap smear",
    "Pap test",
    "Papanicolaou stain"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "cervix"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 789 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/papanicolaou-smear/"
}