Peptide mass fingerprinting

{
  "id": "MLC-T-CHM-008607",
  "term": "Peptide mass fingerprinting",
  "field": "Chemistry",
  "definition": "A protein identification technique where a protein is first digested into smaller peptides using a specific protease, such as trypsin. The resulting peptide mixture is then analyzed by mass spectrometry to generate a list of peptide masses. This 'fingerprint' is compared against theoretical peptide mass lists from protein databases to identify the original protein.",
  "synonyms": [
    "mass mapping"
  ],
  "subject": "Analytical Chemistry",
  "see_also": [
    "accurate mass tag"
  ],
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1576 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/peptide-mass-fingerprinting/"
}