Phospholipase Cγ

{
  "id": "MLC-T-CHM-008779",
  "term": "Phospholipase Cγ",
  "field": "Chemistry",
  "definition": "An enzyme that hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) into inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG). This cleavage initiates a signaling cascade within cells, leading to calcium mobilization and protein kinase C activation. The enzyme is activated by receptor tyrosine kinases and is involved in immune cell signaling.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "lymphocyte activation"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1228 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/phospholipase-cg/"
}