Tyrosine kinase

{
  "id": "MLC-T-CHM-013676",
  "term": "Tyrosine kinase",
  "field": "Chemistry",
  "definition": "An enzyme that catalyzes the transfer of a phosphate group from adenosine triphosphate (ATP) to a tyrosine residue on a protein. This phosphorylation event acts as a molecular switch, regulating many cellular processes such as growth, differentiation, and metabolism. Dysregulation of tyrosine kinase activity is implicated in several diseases, including cancer.",
  "synonyms": [
    "protein tyrosine kinase"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "T lymphocyte",
    "Zeta chain-associated protein kinase-70 kDa",
    "lymphocyte activation"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1257 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tyrosine-kinase/"
}