Plaque-forming cell

{
  "id": "MLC-T-CHM-009004",
  "term": "Plaque-forming cell",
  "field": "Chemistry",
  "definition": "A B lymphocyte that has differentiated into a plasma cell and is actively secreting antibodies. These cells are identified in an assay by their ability to lyse antigen-coated red blood cells in the presence of complement, creating clear zones or plaques. The number of plaque-forming cells indicates the magnitude of an antibody response.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "erythrocyte",
    "anti-sheep red blood cell IgM response assay",
    "plasma cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1229 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/plaque-forming-cell/"
}