Anti-sheep red blood cell IgM response assay

{
  "id": "MLC-T-CHM-000710",
  "term": "Anti-sheep red blood cell IgM response assay",
  "field": "Chemistry",
  "definition": "A common immunotoxicological assay used to assess the functional integrity of the immune system, particularly T-lymphocyte-dependent antibody responses. It measures the production of IgM antibodies against sheep red blood cells (SRBCs) following immunization. This assay is a sensitive indicator of immunosuppression or immunostimulation caused by chemical exposure.",
  "synonyms": [
    "plaque assay",
    "SRBC Assay"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "enzyme-linked immunosorbent assay",
    "tetanus toxoid"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1127 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/anti-sheep-red-blood-cell-igm-response-assay/"
}