Probit log transform

{
  "id": "MLC-T-CHM-009488",
  "term": "Probit log transform",
  "field": "Chemistry",
  "definition": "A statistical transformation applied to dose-response data to linearize the relationship between the logarithm of the dose and the probit of the response. This method is commonly employed in toxicology and pharmacology to estimate parameters such as the median lethal dose (LD50) or median effective dose (ED50). It assumes a normal distribution of individual tolerances to a given substance.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "graded effect",
    "quantal effect"
  ],
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 932 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/probit-log-transform/"
}