Pyknosis

{
  "id": "MLC-T-CHM-009691",
  "term": "Pyknosis",
  "field": "Chemistry",
  "definition": "A morphological change in the nucleus of a cell characterized by the irreversible condensation of chromatin into a dense, shrunken mass. This process is a hallmark of necrosis and apoptosis, indicating cellular degeneration and impending cell death. The pyknotic nucleus often appears as a small, dark, and uniformly stained structure under a microscope.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 900 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/pyknosis/"
}