Quadrupole time-of-flight

{
  "id": "MLC-T-CHM-009727",
  "term": "Quadrupole time-of-flight",
  "field": "Chemistry",
  "definition": "A hybrid mass spectrometry technique combining a quadrupole mass filter with a time-of-flight (TOF) mass analyzer. The quadrupole typically acts as a collision cell for fragmentation or as a pre-filter for ions, while the TOF section provides high-resolution mass analysis. This configuration offers both high mass accuracy and sensitivity, making it suitable for complex mixture analysis.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "hybrid mass spectrometer",
    "collision quadrupole",
    "orthogonal extraction",
    "transmission quadrupole mass spectrometer"
  ],
  "references": [
    "PAC, 2013, 85, 1515. 'Definitions of terms relating to mass spectrometry (IUPAC Recommendations 2013)' on page 1581 (https://doi.org/10.1351/PAC-REC-06-04-06)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/quadrupole-time-of-flight/"
}