Reactive astrocyte

{
  "id": "MLC-T-CHM-013482",
  "term": "Reactive astrocyte",
  "field": "Chemistry",
  "definition": "An astrocyte that undergoes morphological, molecular, and functional changes in response to central nervous system injury or disease. These cells exhibit hypertrophy, increased expression of glial fibrillary acidic protein (GFAP), and altered secretory profiles. Reactive astrocytes contribute to both neuroprotection and neurotoxicity, forming astrocytic scars that can impede axonal regeneration.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "astrocyte",
    "astrocytic scar",
    "glial fibrillary acidic protein"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 850 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reactive-astrocyte/"
}