Rheumatoid factor

{
  "id": "MLC-T-CHM-010340",
  "term": "Rheumatoid factor",
  "field": "Chemistry",
  "definition": "An autoantibody, an antibody directed against the body's own tissues, that is present in the blood of many people with rheumatoid arthritis and other autoimmune diseases. These antibodies target the Fc portion of immunoglobulin G (IgG) molecules, forming immune complexes that contribute to inflammation. While most rheumatoid factors are of the IgM isotype, they can also be IgG or IgA.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Fc fragment",
    "immunoglobulin A",
    "immunoglobulin G",
    "immunoglobulin M",
    "natural autoantibodies",
    "rheumatoid arthritis"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1241 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/rheumatoid-factor/"
}