Tetrahedral intermediate

{
  "id": "MLC-T-CHM-011903",
  "term": "Tetrahedral intermediate",
  "field": "Chemistry",
  "definition": "A transient species formed during nucleophilic acyl substitution reactions, where a nucleophile attacks a carbonyl carbon, leading to a carbon atom that is temporarily bonded to four groups in a tetrahedral geometry. This intermediate is typically short-lived and rapidly collapses to form the product by expelling a leaving group. Its formation is a key step in reactions like ester hydrolysis.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "condensation reaction",
    "intermediate"
  ],
  "references": [
    "PAC, 1994, 66, 1077. 'Glossary of terms used in physical organic chemistry (IUPAC Recommendations 1994)' on page 1173 (https://doi.org/10.1351/pac199466051077)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tetrahedral-intermediate/"
}