Transverse relaxation optimized spectroscopy
Term · Chemistry · MLC-T-CHM-012272
A nuclear magnetic resonance (NMR) technique for studying large macromolecules by reducing the line broadening caused by rapid transverse relaxation. Transverse relaxation optimized spectroscopy (TROSY) works by selectively detecting the one narrow component of a multiplet that experiences cancellation of relaxation effects. This method exploits the interference between dipole-dipole coupling and chemical shift anisotropy relaxation mechanisms, which is most effective at high magnetic field strengths.
| Identifier | MLC-T-CHM-012272 |
|---|---|
| Field | Chemistry |
| Subject | Analytical Chemistry |
| References | PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 709 (https://doi.org/10.1515/pac-2019-0203) |
| See also | Chemical shift anisotropy; Nuclear magnetic resonance spectroscopy; Spin-spin relaxation |
Record as JSON
{
"id": "MLC-T-CHM-012272",
"term": "Transverse relaxation optimized spectroscopy",
"field": "Chemistry",
"definition": "A nuclear magnetic resonance (NMR) technique for studying large macromolecules by reducing the line broadening caused by rapid transverse relaxation. Transverse relaxation optimized spectroscopy (TROSY) works by selectively detecting the one narrow component of a multiplet that experiences cancellation of relaxation effects. This method exploits the interference between dipole-dipole coupling and chemical shift anisotropy relaxation mechanisms, which is most effective at high magnetic field strengths.",
"subject": "Analytical Chemistry",
"see_also": [
"chemical shift anisotropy",
"nuclear magnetic resonance spectroscopy",
"spin-spin relaxation"
],
"references": [
"PAC, 2021, 93, 647. 'Glossary of methods and terms used in analytical spectroscopy (IUPAC Recommendations 2019)' on page 709 (https://doi.org/10.1515/pac-2019-0203)"
],
"url": "https://mlchart.com/terminology/chemistry/transverse-relaxation-optimized-spectroscopy/"
}
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