Arthus reaction

{
  "id": "MLC-T-CHM-000808",
  "term": "Arthus reaction",
  "field": "Chemistry",
  "definition": "A localized type III hypersensitivity reaction characterized by tissue necrosis resulting from the formation of immune complexes in the blood vessel walls. This reaction occurs when a high concentration of antigen is injected into an individual who has pre-existing antibodies. It typically manifests as localized edema, hemorrhage, and necrosis within hours of antigen exposure.",
  "synonyms": [
    "Gell and Coombs Type III reaction"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "Gell and Coombs classification",
    "hypersensitivity",
    "neutrophil"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1128 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/arthus-reaction/"
}