Barton reaction

{
  "id": "MLC-T-CHM-012914",
  "term": "Barton reaction",
  "field": "Chemistry",
  "definition": "A photochemical reaction involving the homolytic cleavage of a nitrite ester to generate an alkoxyl radical, which then undergoes intramolecular hydrogen atom abstraction. This process leads to the formation of a carbon-centered radical, which can subsequently react with nitric oxide. The reaction is particularly effective for the functionalization of unactivated carbon atoms.",
  "subject": "Organic and Biomolecular Chemistry",
  "see_also": [
    "photolysis",
    "abstraction",
    "chemical induction"
  ],
  "references": [
    "PAC, 1996, 68, 2223. 'Glossary of terms used in photochemistry (IUPAC Recommendations 1996)' on page 2229 (https://doi.org/10.1351/pac199668122223)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/barton-reaction/"
}