MLchartDataset catalogue

Bcl-2

Term · Chemistry · MLC-T-CHM-001154

A family of proteins that regulate programmed cell death, or apoptosis. Some members, like Bcl-2 itself, are anti-apoptotic, preventing cell death, while others are pro-apoptotic, promoting it. The balance between these proteins determines whether a cell lives or dies, and dysregulation is implicated in cancers and autoimmune diseases.

Table 1. Record
IdentifierMLC-T-CHM-001154
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1134 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoB lymphocyte; Leukemia
Record as JSON
{
  "id": "MLC-T-CHM-001154",
  "term": "Bcl-2",
  "field": "Chemistry",
  "definition": "A family of proteins that regulate programmed cell death, or apoptosis. Some members, like Bcl-2 itself, are anti-apoptotic, preventing cell death, while others are pro-apoptotic, promoting it. The balance between these proteins determines whether a cell lives or dies, and dysregulation is implicated in cancers and autoimmune diseases.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "leukemia"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1134 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/bcl-2/"
}

Record 1,241 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.