MLchartDataset catalogue

CD25

Term · Chemistry · MLC-T-CHM-001764

The alpha subunit of the interleukin-2 receptor (IL-2Rα), a membrane protein carried by activated T lymphocytes and regulatory T cells. On its own it binds IL-2 weakly, but joined with CD122 (IL-2Rβ) and CD132 (the common gamma chain) it forms the high-affinity receptor, and its presence on a T cell is read as a marker of activation. It is encoded by the IL2RA gene.

Table 1. Record
IdentifierMLC-T-CHM-001764
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1139 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoInterleukin
Record as JSON
{
  "id": "MLC-T-CHM-001764",
  "term": "CD25",
  "field": "Chemistry",
  "definition": "The alpha subunit of the interleukin-2 receptor (IL-2Rα), a membrane protein carried by activated T lymphocytes and regulatory T cells. On its own it binds IL-2 weakly, but joined with CD122 (IL-2Rβ) and CD132 (the common gamma chain) it forms the high-affinity receptor, and its presence on a T cell is read as a marker of activation. It is encoded by the IL2RA gene.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "interleukin"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1139 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cd25/"
}

Record 1,886 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.