Regulatory T cell

{
  "id": "MLC-T-CHM-010127",
  "term": "Regulatory T cell",
  "field": "Chemistry",
  "definition": "A subpopulation of T lymphocytes that actively suppresses the immune response to maintain self-tolerance and prevent autoimmune diseases. These cells modulate the activity of other immune cells, such as effector T cells, to control inflammation and prevent excessive immune reactions. They are characterized by the expression of specific surface markers, including CD4 and CD25, and the transcription factor FOXP3.",
  "synonyms": [
    "natural regulatory T cell"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "CD4+/CD25+ T cell",
    "CD8+ T suppressor cell",
    "T lymphocyte",
    "negative selection",
    "thymic"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1240 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/regulatory-t-cell/"
}