Chronic myelogenous leukemia

{
  "id": "MLC-T-CHM-002063",
  "term": "Chronic myelogenous leukemia",
  "field": "Chemistry",
  "definition": "A type of cancer affecting the blood and bone marrow, characterized by the uncontrolled growth of myeloid cells. This condition is associated with a specific genetic abnormality, the Philadelphia chromosome, which results from a translocation between chromosomes 9 and 22. The presence of this chromosome leads to the production of a fusion protein that drives the proliferation of cancerous cells.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "bone marrow"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1144 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/chronic-myelogenous-leukemia/"
}