Cross-linking

Term · Chemistry · MLC-T-CHM-002720

The process of forming covalent bonds between polymer chains or between different molecules, resulting in a network structure. In biological systems, this can involve linking proteins or nucleic acids, often to stabilize complexes or to study molecular interactions. This technique is frequently used in gel electrophoresis to alter the pore size of the gel matrix.

Table 1. Record
Identifier	MLC-T-CHM-002720
Field	Chemistry
Subject	Analytical Chemistry
References	PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1183 (https://doi.org/10.1515/pac-2016-1120)
See also	Biomacromolecule; Chromatin immunoprecipitation

Record as JSON

{
  "id": "MLC-T-CHM-002720",
  "term": "Cross-linking",
  "field": "Chemistry",
  "definition": "The process of forming covalent bonds between polymer chains or between different molecules, resulting in a network structure. In biological systems, this can involve linking proteins or nucleic acids, often to stabilize complexes or to study molecular interactions. This technique is frequently used in gel electrophoresis to alter the pore size of the gel matrix.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "biomacromolecule",
    "chromatin immunoprecipitation"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1183 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cross-linking/"
}

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