Cyclooxygenase specific inhibitors

{
  "id": "MLC-T-CHM-002825",
  "term": "Cyclooxygenase specific inhibitors",
  "field": "Chemistry",
  "definition": "A class of pharmaceutical agents that selectively block the activity of specific isoforms of the cyclooxygenase (COX) enzyme, primarily COX-2. These inhibitors reduce inflammation, pain, and fever by preventing the synthesis of prostaglandins from arachidonic acid. Unlike non-selective COX inhibitors, they aim to minimize gastrointestinal side effects associated with COX-1 inhibition.",
  "subject": "Chemistry and Human Health",
  "references": [
    "PAC, 2007, 79, 1153. 'Glossary of terms used in toxicology, 2nd edition (IUPAC Recommendations 2007)' on page 1201 (https://doi.org/10.1351/pac200779071153)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cyclooxygenase-specific-inhibitors/"
}