Difference gel electrophoresis

{
  "id": "MLC-T-CHM-003162",
  "term": "Difference gel electrophoresis",
  "field": "Chemistry",
  "definition": "A technique used to compare protein samples by labeling them with different fluorescent dyes before combining and separating them on a single two-dimensional polyacrylamide gel. This allows for precise detection and quantification of differences in protein expression between samples, minimizing gel-to-gel variation. The method typically employs cyanine dyes for labeling.",
  "subject": "Analytical Chemistry",
  "see_also": [
    "two-dimensional gel electrophoresis"
  ],
  "references": [
    "PAC, 2018, 90, 1121. 'Terminology of bioanalytical methods (IUPAC Recommendations 2018)' on page 1155 (https://doi.org/10.1515/pac-2016-1120)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/difference-gel-electrophoresis/"
}