Immunophilin

{
  "id": "MLC-T-CHM-005697",
  "term": "Immunophilin",
  "field": "Chemistry",
  "definition": "A family of intracellular proteins that bind to and mediate the effects of immunosuppressive drugs like cyclosporin A and tacrolimus. These proteins possess peptidyl-prolyl cis-trans isomerase activity, influencing protein folding and signaling pathways within cells. Immunophilins are involved in T lymphocyte activation and are targets for immunosuppressive therapies to prevent transplant rejection.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "immunosuppressant"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1190 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/immunophilin/"
}