MLchartDataset catalogue

Kainic acid

Term · Chemistry · MLC-T-CHM-006296

A potent neuroexcitatory amino acid isolated from the red algae Digenea simplex, structurally related to glutamate. It acts as an agonist at specific glutamate receptors, particularly the kainate receptors, leading to neuronal overstimulation and excitotoxicity. This compound is often used in neuroscience research to induce epileptic seizures or neuronal damage.

Table 1. Record
IdentifierMLC-T-CHM-006296
FieldChemistry
SubjectChemistry and Human Health
Synonyms(2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid
ReferencesPAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 877 (https://doi.org/10.1515/pac-2015-0103)
See alsoExcitotoxicity; Glutamate
Record as JSON
{
  "id": "MLC-T-CHM-006296",
  "term": "Kainic acid",
  "field": "Chemistry",
  "definition": "A potent neuroexcitatory amino acid isolated from the red algae Digenea simplex, structurally related to glutamate. It acts as an agonist at specific glutamate receptors, particularly the kainate receptors, leading to neuronal overstimulation and excitotoxicity. This compound is often used in neuroscience research to induce epileptic seizures or neuronal damage.",
  "synonyms": [
    "(2S,3S,4S)-3-(carboxymethyl)-4-(prop-1-en-2-yl)pyrrolidine-2-carboxylic acid"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "excitotoxicity",
    "glutamate"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 877 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/kainic-acid/"
}

Record 6,683 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.