Γ-aminobutyric acid

{
  "id": "MLC-T-CHM-004747",
  "term": "Γ-aminobutyric acid",
  "field": "Chemistry",
  "definition": "The main inhibitory neurotransmitter of the mammalian central nervous system, an amino acid that is made from glutamate by the enzyme glutamate decarboxylase. Binding to GABA-A receptors opens chloride channels, and binding to GABA-B receptors opens potassium channels through G proteins, so the neuron is hyperpolarized and fires less readily. Its formula is C4H9NO2, and it is not used to build proteins.",
  "synonyms": [
    "4-aminobutanoic acid"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "neurotransmitter",
    "synapse"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 845 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/g-aminobutyric-acid/"
}