N-methyl-D-aspartate-type glutamate receptor

{
  "id": "MLC-T-CHM-013335",
  "term": "N-methyl-D-aspartate-type glutamate receptor",
  "field": "Chemistry",
  "definition": "A specific subtype of ionotropic glutamate receptor that is a ligand-gated ion channel, activated by the binding of glutamate and glycine or D-serine. This receptor is permeable to calcium ions and sodium ions, and its activity is modulated by magnesium ions. It is involved in synaptic plasticity and memory formation in the central nervous system.",
  "synonyms": [
    "NMDA-type glutamate receptor"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "N-methyl-D-aspartate",
    "glutamate",
    "ligand-gated ion channel",
    "neurotransmitter",
    "voltage-gated ion channel",
    "2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid receptor"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 881 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/n-methyl-d-aspartate-type-glutamate-receptor/"
}