Lymphocytotoxicity

{
  "id": "MLC-T-CHM-006838",
  "term": "Lymphocytotoxicity",
  "field": "Chemistry",
  "definition": "The ability of an agent to destroy lymphocytes, for example antibody plus complement lysing lymphocytes that carry a matching surface antigen, or primed histoincompatible T cells attacking them. Lymphocytes are the target cells here, in contrast to lymphocyte-mediated cytotoxicity, where they are the killers. The complement-dependent crossmatch used before organ transplantation tests recipient serum against donor lymphocytes in this way.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "histoincompatibility",
    "lymphocyte",
    "prime"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1206 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/lymphocytotoxicity/"
}