Mantle zone

{
  "id": "MLC-T-CHM-006951",
  "term": "Mantle zone",
  "field": "Chemistry",
  "definition": "The outer layer of a lymphoid follicle, surrounding the germinal center, composed primarily of small, naive B lymphocytes. These cells have not yet been activated by antigen and are in a resting state. The mantle zone is a characteristic feature of secondary lymphoid organs like lymph nodes and spleen.",
  "synonyms": [
    "corona",
    "mantle"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "lymphocyte",
    "lymphoid follicle",
    "lymphoma"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1210 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/mantle-zone/"
}