Mannose-binding protein

{
  "id": "MLC-T-CHM-006950",
  "term": "Mannose-binding protein",
  "field": "Chemistry",
  "definition": "A C-type lectin that recognizes specific carbohydrate patterns on the surface of pathogens, initiating the lectin pathway of the complement system. This protein, also known as mannan-binding lectin, binds to mannose and N-acetylglucosamine residues. Its binding activates associated serine proteases, leading to pathogen opsonization and lysis.",
  "synonyms": [
    "mannose-binding lectin (MBL)"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "acute-phase protein",
    "classical pathway",
    "collectin",
    "phagocytosis"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1210 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/mannose-binding-protein/"
}