P-selectin
Term · Chemistry · MLC-T-CHM-009622
An adhesion molecule stored in the alpha-granules of platelets and in the Weibel-Palade bodies of endothelial cells. Upon activation of these cells by stimuli such as thrombin or histamine, P-selectin is rapidly moved to the cell surface. It mediates the initial tethering of leukocytes and platelets to the endothelium during inflammation and hemostasis.
| Identifier | MLC-T-CHM-009622 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1224 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Adhesion molecule; Platelet |
Record as JSON
{
"id": "MLC-T-CHM-009622",
"term": "P-selectin",
"field": "Chemistry",
"definition": "An adhesion molecule stored in the alpha-granules of platelets and in the Weibel-Palade bodies of endothelial cells. Upon activation of these cells by stimuli such as thrombin or histamine, P-selectin is rapidly moved to the cell surface. It mediates the initial tethering of leukocytes and platelets to the endothelium during inflammation and hemostasis.",
"subject": "Chemistry and Human Health",
"see_also": [
"adhesion molecule",
"platelet"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1224 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/p-selectin/"
}
Record 10,225 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.