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Prosthetic group

Term · Chemistry · MLC-T-CHM-009562

A non-protein chemical component that is tightly and stably bound to a protein, often through covalent bonds, and is required for the protein's biological activity. Unlike some cofactors that bind transiently, a prosthetic group is a permanent part of the protein's structure. The heme group in hemoglobin and cytochromes is a common example of a prosthetic group.

Table 1. Record
IdentifierMLC-T-CHM-009562
FieldChemistry
SubjectChemistry and the Environment
ReferencesPAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 163 (https://doi.org/10.1351/pac199264010143)
See alsoCofactors; Cytochromes; Glycopeptides; Lipids; Lipoproteins; Polysaccharides
Record as JSON
{
  "id": "MLC-T-CHM-009562",
  "term": "Prosthetic group",
  "field": "Chemistry",
  "definition": "A non-protein chemical component that is tightly and stably bound to a protein, often through covalent bonds, and is required for the protein's biological activity. Unlike some cofactors that bind transiently, a prosthetic group is a permanent part of the protein's structure. The heme group in hemoglobin and cytochromes is a common example of a prosthetic group.",
  "subject": "Chemistry and the Environment",
  "see_also": [
    "cofactors",
    "cytochromes",
    "glycopeptides",
    "lipids",
    "lipoproteins",
    "polysaccharides"
  ],
  "references": [
    "PAC, 1992, 64, 143. 'Glossary for chemists of terms used in biotechnology (IUPAC Recommendations 1992)' on page 163 (https://doi.org/10.1351/pac199264010143)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/prosthetic-group/"
}

Record 10,157 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.