Reciprocal translocation

{
  "id": "MLC-T-CHM-013486",
  "term": "Reciprocal translocation",
  "field": "Chemistry",
  "definition": "A chromosomal abnormality resulting from the mutual exchange of segments between two different, non-homologous chromosomes. When the exchange involves no net loss or gain of genetic material, the translocation is considered balanced, and the carrier is typically phenotypically normal. Individuals with a balanced translocation have an increased risk of producing gametes with an unbalanced chromosome complement, which can lead to infertility, spontaneous abortion, or offspring with congenital anomalies.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "chromosomal translocation",
    "homologous"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 799 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/reciprocal-translocation/"
}