Substantia nigra

{
  "id": "MLC-T-CHM-011526",
  "term": "Substantia nigra",
  "field": "Chemistry",
  "definition": "A nucleus in the midbrain, part of the basal ganglia, that has a major role in motor control, reward, and addiction. It is composed of two main parts: the pars compacta, which produces the neurotransmitter dopamine, and the pars reticulata. The progressive loss of dopamine-producing neurons in the pars compacta is the primary pathological hallmark of Parkinson disease, leading to its characteristic motor symptoms.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "dopamine",
    "neurotransmitter",
    "Parkinson disease"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 908 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/substantia-nigra/"
}