Thalidomide

{
  "id": "MLC-T-CHM-011919",
  "term": "Thalidomide",
  "field": "Chemistry",
  "definition": "A synthetic drug that gained notoriety in the late 1950s and early 1960s for causing severe birth defects, particularly phocomelia, when taken by pregnant women. It was originally marketed as a sedative and antiemetic. Despite its teratogenic effects, it has found renewed use in treating certain conditions like multiple myeloma and leprosy due to its immunomodulatory and anti-angiogenic properties.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "teratogen",
    "angiogenesis",
    "birth defect",
    "phocomelia",
    "pregnancy"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 812 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/thalidomide/"
}