Tr1 cell

{
  "id": "MLC-T-CHM-012185",
  "term": "Tr1 cell",
  "field": "Chemistry",
  "definition": "A type of regulatory T lymphocyte that produces high levels of interleukin-10 (IL-10) and transforming growth factor-beta (TGF-β), cytokines that suppress immune responses. These cells are involved in maintaining immune tolerance and preventing autoimmune diseases. Tr1 cells can be induced in vitro and in vivo under specific cytokine conditions.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T lymphocyte",
    "Th1 cell",
    "Th3 cell",
    "regulatory T cell",
    "immunological tolerance"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1251 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/tr1-cell/"
}