Western Pacific amyotrophic lateral sclerosis and parkinsonism-dementia complex

{
  "id": "MLC-T-CHM-012680",
  "term": "Western Pacific amyotrophic lateral sclerosis and parkinsonism-dementia complex",
  "field": "Chemistry",
  "definition": "A neurodegenerative disorder endemic to certain Western Pacific islands, characterized by a combination of symptoms resembling amyotrophic lateral sclerosis, Parkinson's disease, and dementia. The etiology is complex, with environmental factors, such as exposure to cycad neurotoxins, being implicated. This condition presents a unique clinical profile distinct from sporadic forms of these diseases.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "neurodegenerative disease",
    "neurotoxin",
    "dementia",
    "Parkinson disease",
    "tauopathy"
  ],
  "references": [
    "PAC, 2015, 87, 841. 'IUPAC Glossary of terms used in neurotoxicology (IUPAC Recommendations 2015)' on page 916 (https://doi.org/10.1515/pac-2015-0103)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/western-pacific-amyotrophic-lateral-sclerosis-and-parkinsonism-dementia-complex/"
}