Decidual cell response technique

{
  "id": "MLC-T-CHM-002902",
  "term": "Decidual cell response technique",
  "field": "Chemistry",
  "definition": "A bioassay used to evaluate the uterus's capacity for decidualization, a key process for embryo implantation. The method involves hormonally preparing a non-pregnant female animal, typically a rodent, to mimic the endocrine state of early pregnancy and then applying a physical or chemical stimulus to the uterine lining. The resulting growth and differentiation of endometrial stromal cells into decidual cells is then measured to assess the effects of potential reproductive toxicants on this transformation.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "blastocyst",
    "decidua",
    "decidual cell",
    "hormone",
    "implantation",
    "pseudopregnancy",
    "uterus"
  ],
  "references": [
    "PAC, 2016, 88, 713. 'Glossary of terms used in developmental and reproductive toxicology (IUPAC Recommendations 2016)' on page 742 (https://doi.org/10.1515/pac-2015-1202)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/decidual-cell-response-technique/"
}