γ:δ T-cell receptor

{
  "id": "MLC-T-CHM-004788",
  "term": "γ:δ T-cell receptor",
  "field": "Chemistry",
  "definition": "A heterodimeric protein complex found on the surface of γ:δ T cells, consisting of one gamma (γ) and one delta (δ) polypeptide chain. This receptor is involved in recognizing a broad spectrum of antigens, including phospholipids, alkyl amines, and heat shock proteins, often in a major histocompatibility complex (MHC)-independent manner. The structure and antigen recognition mechanisms differ significantly from the α:β T-cell receptor.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "T-cell receptor",
    "intra-epithelial lymphocyte",
    "lymphocyte",
    "mucosa",
    "α:β T cell",
    "γ:δ T cell"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1167 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/g-d-t-cell-receptor/"
}