Ligand of inducible co-stimulatory protein

{
  "id": "MLC-T-CHM-006571",
  "term": "Ligand of inducible co-stimulatory protein",
  "field": "Chemistry",
  "definition": "A protein expressed on antigen-presenting cells that binds to the inducible co-stimulatory protein (ICOS) found on activated T cells. This interaction provides a co-stimulatory signal that promotes T cell proliferation and cytokine production. The binding of this ligand to ICOS is involved in regulating immune responses, particularly in autoimmune diseases and allergic reactions.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "allergy",
    "autoimmunity",
    "graft-versus-host reaction",
    "inducible co-stimulatory protein"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1202 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/ligand-of-inducible-co-stimulatory-protein/"
}