MLchartDataset catalogue

Polyclonal activator

Term · Chemistry · MLC-T-CHM-009118

A substance that stimulates a large proportion of lymphocytes, both B and T cells, to proliferate and differentiate, regardless of their antigen specificity. These activators bypass the need for specific antigen recognition, leading to a broad, non-specific immune response. Pokeweed mitogen and lipopolysaccharide are examples of polyclonal activators.

Table 1. Record
IdentifierMLC-T-CHM-009118
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1231 (https://doi.org/10.1351/PAC-REC-11-06-03)
See alsoB lymphocyte; T lymphocyte; Lymphocyte activation; Mitogen
Record as JSON
{
  "id": "MLC-T-CHM-009118",
  "term": "Polyclonal activator",
  "field": "Chemistry",
  "definition": "A substance that stimulates a large proportion of lymphocytes, both B and T cells, to proliferate and differentiate, regardless of their antigen specificity. These activators bypass the need for specific antigen recognition, leading to a broad, non-specific immune response. Pokeweed mitogen and lipopolysaccharide are examples of polyclonal activators.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "T lymphocyte",
    "lymphocyte activation",
    "mitogen"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1231 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/polyclonal-activator/"
}

Record 9,683 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.