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Toxicity value

Term · Chemistry · MLC-T-CHM-012169

A numerical factor that regulators use to estimate risk from an exposure, such as a reference dose or reference concentration for threshold effects, or a slope factor or unit risk that links dose to the probability of cancer. It is derived from a dose-response relationship, usually after applying uncertainty factors to a no-observed-adverse-effect level or benchmark dose. Multiplying a slope factor by an exposure estimate gives an estimate of lifetime cancer risk.

Table 1. Record
IdentifierMLC-T-CHM-012169
FieldChemistry
SubjectChemistry and Human Health
ReferencesPAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 958 (https://doi.org/10.1351/PAC-REC-08-07-09)
See alsoDose-effect relationship
Record as JSON
{
  "id": "MLC-T-CHM-012169",
  "term": "Toxicity value",
  "field": "Chemistry",
  "definition": "A numerical factor that regulators use to estimate risk from an exposure, such as a reference dose or reference concentration for threshold effects, or a slope factor or unit risk that links dose to the probability of cancer. It is derived from a dose-response relationship, usually after applying uncertainty factors to a no-observed-adverse-effect level or benchmark dose. Multiplying a slope factor by an exposure estimate gives an estimate of lifetime cancer risk.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "dose-effect relationship"
  ],
  "references": [
    "PAC, 2009, 81, 829. 'Glossary of terms used in ecotoxicology (IUPAC Recommendations 2009)' on page 958 (https://doi.org/10.1351/PAC-REC-08-07-09)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/toxicity-value/"
}

Record 12,975 of 13,676 in Chemistry terminology (MLC-0109). Request the full dataset.