Unresponsiveness

{
  "id": "MLC-T-CHM-012452",
  "term": "Unresponsiveness",
  "field": "Chemistry",
  "definition": "A state in which the immune system fails to mount a protective or damaging response to an antigen, despite prior exposure. This condition can be induced experimentally or occur naturally, representing a form of immunological tolerance. It is a key mechanism in preventing autoimmune diseases and in the success of organ transplantation.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "antigenic",
    "immune system",
    "immunological tolerance"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1257 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/unresponsiveness/"
}