B-1/B-2 cells

{
  "id": "MLC-T-CHM-001061",
  "term": "B-1/B-2 cells",
  "field": "Chemistry",
  "definition": "Two distinct subsets of B lymphocytes, differing in their developmental origin, location, and functional characteristics. B-1 cells are found primarily in the peritoneal and pleural cavities and produce natural antibodies, while B-2 cells are the conventional B cells found in lymphoid organs and are responsible for T-cell dependent antibody responses. B-2 cells express CD23, whereas B-1 cells do not.",
  "synonyms": [
    "B-1/B-2 lymphocytes"
  ],
  "subject": "Chemistry and Human Health",
  "see_also": [
    "B lymphocyte",
    "CD23",
    "bone marrow",
    "immunoglobulin D",
    "immunoglobulin M"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1132 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/b-1-b-2-cells/"
}