Coombs test
Term · Chemistry · MLC-T-CHM-002552
A laboratory test used to detect antibodies that bind to the surface of red blood cells. The direct Coombs test identifies antibodies already attached to erythrocytes, while the indirect Coombs test detects free antibodies in the serum that could bind to red blood cells. This test is routinely used in blood transfusions and in diagnosing autoimmune hemolytic anemia.
| Identifier | MLC-T-CHM-002552 |
|---|---|
| Field | Chemistry |
| Subject | Chemistry and Human Health |
| Synonyms | direct antiglobulin test (DAT); direct Coombs test; indirect antiglobulin test (IAT); indirect Coombs test |
| References | PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1149 (https://doi.org/10.1351/PAC-REC-11-06-03) |
| See also | Antigenicity; Erythrocyte |
Record as JSON
{
"id": "MLC-T-CHM-002552",
"term": "Coombs test",
"field": "Chemistry",
"definition": "A laboratory test used to detect antibodies that bind to the surface of red blood cells. The direct Coombs test identifies antibodies already attached to erythrocytes, while the indirect Coombs test detects free antibodies in the serum that could bind to red blood cells. This test is routinely used in blood transfusions and in diagnosing autoimmune hemolytic anemia.",
"synonyms": [
"direct antiglobulin test (DAT)",
"direct Coombs test",
"indirect antiglobulin test (IAT)",
"indirect Coombs test"
],
"subject": "Chemistry and Human Health",
"see_also": [
"antigenicity",
"erythrocyte"
],
"references": [
"PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1149 (https://doi.org/10.1351/PAC-REC-11-06-03)"
],
"url": "https://mlchart.com/terminology/chemistry/coombs-test/"
}
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