Cryoglobulin

{
  "id": "MLC-T-CHM-002744",
  "term": "Cryoglobulin",
  "field": "Chemistry",
  "definition": "An antibody or a complex of immunoglobulins in the blood serum that reversibly precipitates at temperatures below normal body temperature (37 °C) and redissolves upon warming. The presence of these proteins can lead to cryoglobulinemia, a condition that may cause inflammation of small blood vessels (vasculitis), joint pain, and kidney damage. Cryoglobulins are classified into three types based on their monoclonal or polyclonal immunoglobulin composition.",
  "subject": "Chemistry and Human Health",
  "see_also": [
    "autoantibody",
    "autoimmune disease",
    "cryoglobulinemic vasculitis",
    "glomerulonephritis",
    "lymphoproliferation",
    "rheumatoid factor"
  ],
  "references": [
    "PAC, 2012, 84, 1113. 'IUPAC glossary of terms used in immunotoxicology (IUPAC Recommendations 2012)' on page 1152 (https://doi.org/10.1351/PAC-REC-11-06-03)"
  ],
  "url": "https://mlchart.com/terminology/chemistry/cryoglobulin/"
}